New research suggests that commonly used sugar substitutes might be linked to faster cognitive decline, particularly in memory and thinking skills. A study published in the journal Neurology analyzed data from nearly 13,000 adults and found that those who consumed the most low- and no-calorie sweeteners showed significantly faster declines compared to those who consumed the least.
The study examined seven popular sweeteners – aspartame, saccharin, acesulfame-K, erythritol, xylitol, sorbitol, and tagatose – which are often found in diet sodas, flavored waters, yogurts, and other ultra-processed foods. Researchers noted that the association was especially pronounced among individuals with diabetes.
After tracking participants for about eight years, researchers discovered that the group consuming the highest amount of sweeteners experienced a 62% faster decline in overall thinking and memory abilities. This is equivalent to about 1.6 years of additional cognitive aging. Even moderate consumption was associated with a 35% faster decline.
Interestingly, the link between sweeteners and cognitive decline was stronger in adults under 60 and in those with diabetes. Six of the seven sweeteners studied showed an association with faster cognitive decline, with tagatose being the exception, though researchers caution this doesn't mean tagatose is necessarily safer.
While the study highlights a significant association, it's important to note that it doesn't prove a direct cause-and-effect relationship. Researchers are urging for more studies to confirm these findings and investigate whether other natural sugar alternatives might be better options for long-term brain health.